The EU has established a roadmap for transitioning to a low-carbon economy, which includes (i) advancing clean technologies and low-carbon energy, (ii) reducing resource consumption, (iii) enhancing energy security, and (iv) improving public health. As a result, there is a significant need for methods that evaluate the environmental, economic, and societal impacts of actions taken at both industrial and policy levels. To address this need, Hasselt University, with support from KU Leuven, the University of Antwerp, EURECA-PRO are jointly organizing the interdisciplinary PhD expert course on the state-of-the-art sustainability assessment tools: Techno-Economic Assessment (TEA), Life Cycle Assessment (LCA), and Real Options analysis (ROA).